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Your Position: Home > SIRP gamma

SIRP gamma

Brief Information

Name:Teratocarcinoma-derived growth factor 1
Target Synonym:CR-1,CRIPTO,Teratocarcinoma-Derived Growth Factor 1,CRGF,Epidermal Growth Factor-Like Cripto Protein CR1,CR,TDGF1,Cripto-1 Growth Factor
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Pending

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Cat. No. Species Product Description Structure Purity Feature
SIG-H82E3 Human Biotinylated Human SIRP gamma / CD172g Protein, His,Avitag™ (MALS verified)
SIG-H82E3-structure
SIG-H82E3-sds
SIG-H5253 Human Human SIRP gamma / CD172g Protein, Fc Tag
SIG-H5253-structure
SIG-H5253-sds
ACRO Quality

Part of Bioactivity data

SIG-H5253-ELISA
SIRP gamma ELISA

Immobilized Human CD47, His Tag (Cat. No. CD7-H5227) at 5 μg/mL (100 μL/well) can bind Human SIRP gamma, Fc Tag (Cat. No. SIG-H5253) with a linear range of 20-312 ng/mL (QC tested).

Protocol
SIG-H82E3-MALS-HPLC
SIRP gamma MALS images

The purity of Biotinylated Human SIRP gamma, His,Avitag (Cat. No. SIG-H82E3) is more than 90% and the molecular weight of this protein is around 45-57 kDa verified by SEC-MALS.

Synonym Name

SIRPG,CD172g,SIRPB2,SIRP-gamma,SIRP-b2,SIRP-beta-2,Cripto-1

Background

Signal-regulatory protein gamma (SIRPG or SIRP-gamma) is also known as CD172 antigen-like family member B (CD172g), Signal-regulatory protein beta-2 (SIRPB2), is a single-pass type I  membrane protein. SIRPG is expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. SIRPG interacts with CD47. On binding with CD47, CD172g mediates cell-cell adhesion.

Clinical and Translational Updates

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